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Fig. 7. Fgf signaling is required for expression of Pea3 and Erm in the somites. Whole-mount in situ hybridization for Pea3 (A,B) or Erm (C,D) on trunks cultured for 24 hours with either DMSO (control) (A,C) or 30 µM SU5402 (B,D). (E-G) Whole mount in situ hybridization for Fgf8 (E), Pea3 (F) or Scx (G) in HH stage 17 embryos; somite stages VII, XII and XVI are indicated. (H-J) Section in situ hybridization for Fgf8 (H), Pea3 (I) or Scx (J) on alternate frontal sections of somite stages XII and XIII in a stage 17 embryo. (J) Red and blue arrows, indicate dermomyotomal and sclerotomal Scx, respectively.





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