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Fig. 2. Neuronal expression of Sra-1. Confocal images of mount preparations for
Sra-1 expression (green) and axonal markers 24B10 or BP102 (red). The merge
channel is shown on the right. (A) During embryogenesis Sra-1 (green)
accumulates in the neuropile of the central nervous system, which also
expresses the BP102 epitope. (B) In the optic ganglia of third instar larval
brains Sra-1 protein expression can be detected in the medulla (md) and
photoreceptor axons that traverse the lamina (la). An intense label can be
seen in the termination zone of the photoreceptor axons R1-R6 in the lamina
(star). The growth cones of these axons also express high levels of the 24B10
antigen (red). (C) Cell bodies of the photoreceptor neurons also express
Sra-1, albeit at lower levels (arrowhead). ed, eye imaginal disc; os, optic
stalk.
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