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Fig. 8. Genetic interaction between sra-1, kette and wasp. (A-H)
Morphology of microchaete on the thorax in different genetic backgrounds.
Quantitative analyses are shown in I. (A) Wild-type flies are characterized by
an ordered array of microchaete, which are normally thin, straight and have a
pointed end. (B) Following expression of one copy of the
UAS-Sra-1Myr transgene in the scabrous pattern, shorter
and split bristles develop (arrow). (C) The same phenotype is observed after
expression of membrane tethered Kette protein (arrow). (D) Co-expression of
both membrane-tethered Sra-1 and Kette leads to a synergistic increase of
bristle defects. (E) Same genetic background as in B but lacking one copy of
the kette gene. The bristle phenotype evoked by Sra-1Myr
expression is not affected. (F) Same genetic background as in B but lacking
one copy of the wasp gene. The bristle phenotype evoked by
Sra-1Myr expression is suppressed. (G) Expression of a
UAS-Sra-1
CMyr transgene in the scabrous pattern
results in loss of bristles. (H) When flies co-express
UAS-Sra-1CMyr and UAS-KetteMyr transgenes, the
loss of bristle phenotype is suppressed. However, bristles are brushed, which
corresponds to the KetteMyr phenotype. (I) Quantitative analyses of
the above-mentioned phenotypes. Threehundred microchaete were counted in each
case.
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