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Fig. 6. Specific changes in gene expression in skin of
Hr-/-mice. (A) Northern analysis of total RNA extracted
from backskin of P12 mice using the indicated probes. casp-14, caspase 14;
calm-4, calmodulin 4/Scarf. ß-Tubulin shows equal RNA loading on
a representative blot. (B) Developmental expression of K10, loricrin,
filaggrin and caspase 14. Northern analysis of RNA prepared from the skin of
mice at indicated ages with the designated probes. ß-Tubulin is shown as
an RNA loading control. +/+, wild type; -/-, Hr-/-.
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