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Fig. 1. Vax1 expression in the ventral telencephalon. (A-D,F) In situ
hybridization revealing Vax1 expression in telencephalic coronal
sections in E12.5 wild-type mice. H is a magnification of F. (A-D) Different
rostrocaudal levels of the same brain (A is the most rostral and D is the most
caudal). Vax1 is strongly expressed in the SA, LGE, MGE and
post-optic area. There is sharp downregulation of Vax1 expression at
the corticostriatal boundary (arrowhead in A). (E) Immunohystochemical
localization of the cell cycle marker Ki67 on an adjacent section to that
shown in F. G is a magnification of E. (E-H) In the ganglionic eminences (F)
and in the septum (H), Vax1 expression overlaps with Ki67 (E,G) with
an inverse gradient. III, third ventricle; AEP, anterior entopeduncular area;
CGE, caudal ganglionic eminence; LGE, lateral ganglionic eminence; MGE, medial
ganglionic eminence; POA, pre-optic area; HT, hypothalamus; SA, septal area.
Scale bars: 500 µm in A-D; 200 µm in E,F; 100 µm in G,H.