|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 7. (A) Model for maintenance of the apical PCP protein complex (prior to PCP
signaling, e.g. anterior to MF). Known physical interactions are highlighted
in blue (this work) (Tree et al.,
2002; Jenny et al.,
2003). The predicted Fmi-mediated complex, containing also Fz,
Stbm and Dsh, is stable when either Dgo or Pk are removed, but unstable in the
double mutant. (B) Proposed model for PCP signaling circuitry during PCP
signaling, e.g. in R3/R4 cells. Fmi is maintained through Dgo function in R3
and Stbm/Pk in R4. Known physical interactions are in blue
(Jenny et al., 2003;
Tree et al., 2002). Factors
depicted in gray are downregulated through PCP signaling at this stage. See
text for details.
|
