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Fig. 8. Cell-specific role of glide. Repo and Stripe co-immunolabelling on
wild-type (A-C), ptc::glide (D-F) and en::glide (G-I)
embryos, lateral views at stage 15. (J) Anti-Repo labelling on
en::glide2 embryos. (B) Central and peripheral glia are indicated by
yellow and white brackets, respectively. In wild-type embryos, Stripe (A) and
Repo (B) are expressed in distinct cells (C). In ptc::glide embryos,
ectopic glide only induces Repo expression (arrows in E) whereas
en::glide embryos show ectopic expression of both Repo (arrows in H)
and Stripe (bracket in G). Note that only few cells coexpress the two markers
(yellow nuclei shown by arrowheads in I). (J) Ectopic expression of
glide2 induces Repo (arrow in J). Dorsal to the top. (K) Summary of
glide and glide2 gain-of-function (gof) phenotypes in the
epidermis. +++ and + symbols indicate, respectively, high or medium potential
to induce tendon cell or glial markers. Arrows in (A) indicate non-specific,
tracheal, labelling. Scale bar: 50 µm.
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