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Fig. 1. Phylogenetic analysis and comparison of deduced amino acid sequences of the
Sp family. (A) The deduced amino acid sequences of mouse Sp genes together
with Drosophila btd and Drosophila Sp1 are analyzed by
CLUSTAL-W program. (B) Amino acid sequence alignment of the conserved region
of the Sp family, from the btd domain to the Zn-finger domain.
Identical residues, when compared with Sp9, are indicated by dots. Gaps in the
sequence, indicated by dashes, are introduced to improve sequence alignment.
The btd domain and Zn-finger domains are indicated by lines above the
amino acid sequences. (C) Alignment of deduced amino acid sequences of
Sp8 and Sp9 from human (Homo sapiens, Hs), mouse
(Mus musculus, Mm), chick (Gallus gallus, Gg) and zebrafish
(Danio rerio, Dr). The btd domain and the Zn-finger domains
are indicated by lines.
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