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Fig. 4. Expression of sp8 and sp9 in the fin bud was
downregulated in the zebrafish mutants with fin defects. (A-C) Dorsal views of
the expression pattern of sp8 at 40 hpf. (D-F) Dorsal views of the
expression pattern of sp9 at 40 hpf. (A) Expression of sp8
in the pectoral fin bud of a wild type embryo (black arrowheads). The
expression in the pectoral fin bud was downregulated (red arrowheads) in
hst (B) and dak (C) mutants, while a normal expression in
the neural tube was still detected. (D) Expression of sp9 in the
pectoral fin bud (black arrowhead) of a wild-type embryo. The expression in
the pectoral fin bud was downregulated (red arrowheads) in hst (E)
and dak (F) mutants, while a normal expression in the brain was still
detected.
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