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Fig. 5. Lack of Gata2 and Gata3 expression in
Phox2b/ mice. The expression of
Gata2 and Gata3 was studied in E13.5 Phox2bLacZ/+
and Phox2bLacZ/LacZ mouse embryos. In the Phox2b knockout
Gata2 (B) and Gata3 (D) were not detectable, by contrast to
the heterozygotes (A,C). Sympathetic ganglion precursors could be detected at
the dorsal aorta in both Phox2b+/ (E) and
Phox2b/ (F) embryos by LacZ staining.