spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 5. Cubn is not localized to the apical cell surface in Amn-deficient KPT. Immunohistochemical analyses of serial paraffin sections (A,D,G) from an adult chimeric kidney with high contribution of Amn-/- cells. Two sets of serial high magnification views are shown in B,E,H and C,F,I. (A-C) Cubn, (D-F) Amn and (G-I) megalin antibody staining of wild-type KPT (blue asterisks; WT) and Amn-deficient KPT (red asterisks; mut). A chimeric tubule (green asterisks; ch), which contains both wild-type and Amn-/- cells, is designated as well as a distal tubule (yellow asterisks; DT). Of significance, Cubn does not localize to the apical surface in Amn-deficient KPT but is observed in the cytoplasm (B,C).





Right arrow Return to article