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Fig. 5. The N terminus is necessary and sufficient for Dup degradation in follicle cells of the ovary. (A) Schematic of Myc-tagged wild-type and mutant Dup transgenes expressed using the hsp70 promoter. The N terminus has ten putative phosphorylation sites (ball and stick, consensus shown above). (B-E) Follicle cells of stage 8 egg chambers expressing different Myc-tagged Dup proteins double labeled for Myc (green) and BrdU (red). (B) Myc:FL-Dup, (C) Myc:Dup 10(A), (D) Myc:N-Dup, (E) Myc:C-Dup. Only C-Dup had significant overlap between Myc and BrdU labeling (yellow). Images are composites of confocal sections. Scale bar: 10 µm (B-E).





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