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Fig. 10. Cdc25B overexpression, but not PDE3A overexpression, overcomes the meiotic
block induced by PTPN13 siRNA. Ten nanograms of siRNA-1, scrambled siRNA-1 or
vehicle were injected into Xenopus oocytes. After 12 hours, oocytes
were stimulated with (A) 500 nM progesterone, or injected with (B) 1 ng of
Cdc25B mRNA or (C) 20 ng of PDE3A mRNA to induce oocyte maturation, and
resumption of meiosis was scored. Results shown are representative of the two
experiments performed.
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