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Fig. 6. Hindlimb-specific, bilateral distal digit duplication in Tbx2^tm1Pa/Tbx2^tm1Pa mutants (–/–). (A) Right view of a dead homozygous mutant embryo (with tail removed) collected at 14.5 dpc. (B) High magnification view of the embryo in A showing a distal duplication of digit IV in the hindlimb. (C) Dorsal view of an Alcian Blue-stained right hindlimb from a dead embryo dissected at 14.5 dpc, showing duplicated cartilage condensations (arrowheads) within the first phalangeal segment of digit IV.

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