|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 5. The MESD chaperone protein increases the membrane localization and
signaling activity of LRP6. (A) MESD increases the membrane localization of
LRP6. LRP6 and LRP6
N were fused with YFP at their C termini, and
expressed in 293 cells with or without co-expression of MESD. The subcellular
localization of wild-type and mutant LRP6 was examined by confocal
fluorescence microscopy. (B) MESD increases the signaling activity of LRP6.
293 cells were transfected with the indicated plasmids together with TOP-FLASH
and CMV-Renilla. The luciferase activities were normalized for
Renilla luciferase activities.
|
