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Fig. 1. Progressive pigmentation in or^J retinas. (A-H) Eyes were sectioned to analyze for pigmentation in or^J/+ heterozygous (A,C,E) or or^J/or^J homozygous (B,D,F,G,H) littermates. Ages are indicated on the figure. (A,B) Insets show a full section of the eye (note scale bar differences). (B,D,F) Arrows indicate the central limit of ectopic pigmentation in the retinas of or^J mutants. (D) The lens is marked by a thin black line in the or^J eye at E17.5. (G,H) The peripheral retina in or^J mutants shows ectopic pigmentation, increasing over time until most of the retina appears pigmented at P15. (H) The presumptive retina is marked with arrowheads. Scale bar is 100 µm.

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