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Fig. 8. ß-Catenin overexpression rescues NC delamination in noggin-treated
neural tubes. (A,B) Neural tubes that received (A) GFP only or (B)
ß-catenin/GFP were placed onto monolayers of control CHO cells (control).
(C,D) Neural tubes that received (C) GFP only or (D) ß-catenin/GFP were
placed onto monolayers of noggin-producing CHO cells. GFP+NC cells (green)
that incorporated BrdU (red) emigrated from the neural primordia onto the
substrates in A,B,D, but not in C. CHO cells on the substrate have background
fluorescence that is clearly distinct from the vibrant green fluorescence of
the electroporated progenitors. Scale bar: 20 µm.
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