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Fig. 8. Round cells retain the capacity to restore dystrophin in myofibers of mdx
nude mice. Five thousand round cells derived from GFP-transgenic mice were
transplanted into gastrocnemius muscles of mdx nude mice pre-treated with CTX.
The muscles were removed 28 days after transplantation and subjected to
immunofluorescence analysis with antibodies to GFP (B) and dystrophin (C).
Immunofluorescence analysis with antibodies to dystrophin revealed the absence
of revertant myofibers in muscles that were treated with CTX alone (A). Scale
bars: 20 µm.
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