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Fig. 4. Excess of cell proliferation in irradiated hh-Gal4>UAS-p35 UAS-GFP wing discs. (A-B) BrdU incorporation in a disc irradiated 48 hours before fixation. BrdU levels are clearly higher in the P compartment, but note that there is also an increase of BrdU in the A compartment cells close to the AP border. (C-D) Disc from the same treatment but stained for phospho-histone 3 (PH3), showing a higher number of mitotic cells in the P compartment. (E-F) Discs of the same genotype also showing increased BrdU incorporation in the P compartment and in zones of the A compartment close to the AP border.





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