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Fig. 3. Pericytes and endothelial cells within the sciatic nerve are not neural
crest derived. Sciatic nerves were dissected from P11
Wnt1-CreloxpRosa+ and
Wnt1-Cre+loxpRosa+ pups, and immunohistochemically
stained for ß-gal (green), the endothelial marker PECAM1 (blue), and the
pericyte marker SMA (red). Although most cells in the endoneurial space were
ß-gal+, both the PECAM1+ endothelial cells and the
SMA+ pericytes consistently failed to co-label with ß-gal.