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Fig. 6. Model of the roles of sal and svp in the specification of
R3/R4 versus R7 [based on our present findings and on Domingos et al.
(Domingos et al., 2004)].
sal is expressed in R3/R4 from row three to row seven, after which it
is progressively repressed. sal expression in R7 starts from row
seven to nine. Expression of svp in R3/R4 starts in row four. From
row three to row seven, sal is required for svp expression
in R3/R4, for R3/R4 specification and for PCP establishment. After rows seven
to nine, sal is necessary and sufficient for R7 differentiation.
Repression of sal by svp in R3/R4 is necessary for the
maintenance of R3/R4 identity and the inhibition of R7 fate.
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