spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 6. Impaired hypertrophic differentiation but normal proliferation in coll2a1-Cre, Fosl2f/f mice. (A,B) In situ hybridization of femoral growth plates of P5, P10 and P23 coll2a1-Cre, Fosl2f/f mice and littermate controls using type X collagen (A) and type II collagen (B) antisense probes. Arrowheads indicate size of proliferating zone. (C) Ki67-positive cells in femoral growth plates of Fosl2–/–, coll2a1-Cre, Fosl2f/f and control mice at P2, P5 and P10. Bars represent mean value±s.e.m.; n=3. (D) Immunohistochemical detection of Ki67 in P23 coll2a1-Cre, Fosl2f/f mice and P23 coll2a1-Cre, Fosl2f/+ controls. Pictures were taken at 50x (col X, P10 and P23; col II, P5 and P10) and 100x (col X, P5; col II, P23; Ki67) magnification.





Right arrow Return to article