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Fig. 5. Gene structures of the ncr-1 and ncr-2 loci and reporter
constructs. (A) Structure of ncr-1A and ncr-1B cDNA
isoforms. Black boxes represent coding and white boxes represent non-coding
exon sequences. The genomic subclone represented by ncr-1A rescued
the ncr-2; ncr-1 Daf-c phenotype. Also shown are corresponding
positions of the original nr2022 deletion allele and additional
mutations isolated from our noncomplementation screen. (B) Structure of
ncr-1 reporter constructs and corresponding expression patterns. (C)
Structure of ncr-2-coding region and position of nr2023
deletion allele. The corresponding genomic fragment rescued the ncr-2;
ncr-1 Daf-c phenotype. (D) Structure of the ncr-2 reporter
construct and its expression pattern.
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