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Fig. 7. Dpr synergizes with Dvl-interacting kinases in Xenopus animal caps. For all injections, unless noted, 1 ng of dpr1, 0.1 ng of ck1 ${epsilon}$ , 0.1 ng of ck1-DN, 1 ng of par1, 2 ng of par1-KN, 0.4 ng of dvl2, 1 ng of ck2 ${alpha}$ , 1 ng of ck2ß, 1 ng of gbp, 1 ng of ß-galactosidase, 0.5 ng of dvl ${Delta}$ pgb RNA were used. Low dose of dpr1 RNA is 0.5 ng for B and E. (A) Dvl2 synergizes with Dpr1, CK1 ${epsilon}$ , CK2, GBP and Par1. (B) Zebrafish Dpr1 synergizes with CK1 ${epsilon}$ , but not CK1-D $->$ N. (C) CK2 can synergize with Dpr1 (Dvl2 is shown as a positive control). (D) Dpr1 synergizes with Par1, but not Par1-KN. Low dose of dpr1 RNA is 0.5 ng. (E) Dpr1 does not synergize well with GBP. (F) Dpr1 does not synergize with the Dvl2 ${Delta}$ PGB.

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