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Fig. 8. Model for the relationship between Notch, EMC and EYA during oogenesis.
Left: in polar/stalk precursors, an unknown pathway (X) inhibits expression of
EMC. In the absence of EMC, EYA is reduced. Right: in main body precursors,
Notch promotes EMC expression, and EMC promotes EYA expression, leading to
either the establishment or maintenance of main body cell identity. In
addition, EMC activity promotes differentiation.
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