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Fig. 2. COUP-TFI is expressed in GABAergic interneurons, while COUP-TFII is
expressed in Cajal-Retzius cells. Double immunofluorescence of COUP-TFs
(green) and cell-type-specific markers (red) in coronal sections of E13.5
(A-G) and E15.5 (H,I) mouse brains. COUP-TFI (A,B), but not COUP-TFII (D,E),
co-labels with calbindin in the MZ of the ncx (A,D) and of the pcx (B,E).
COUP-TFII (F,G,H), but not COUP-TFI (C,I) co-labels with reelin in the MZ of
the neocortex (C,F) and in the caudomedial cortical wall (G-I). The inset in G
is a schematic diagram of the section, and indicates the position of panels
(G-I). The arrows indicate double-positive cells. Note that in H, all the
cells are double positive, while in I none of the cells are double positive.
MZ, marginal zone; ncx, neocortex; pcx, piriform cortex.
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