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Fig. 1. Dynamic expression of Lim1 during Müllerian duct formation. (A-F) Lim1tlz expression in the developing urogenital system. Cranial mesonephric region at E11.5 (A) and E12.0 (B). Ventral view at E12.5 (C) and at E13.5 in females (E) and males (F). Cross-section of the anterior mesonephric region at E12.5 counterstained with Eosin (D). (G,H) Lim1 expression detected using whole-mount in situ hybridization at E12.5 (G) and E13.5 (H) in the female genital system. Asterisks point to the posterior end of the Müllerian duct and broken lines indicate the gonad. g, gonad; k, kidney (metanephros); m, mesonephros; md, Müllerian duct; wd, Wolffian duct. Scale bars: 250 µm in A-C,G,H; 100 µm in D; 500 µm in E,F.





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