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Fig. 8. Precocious patterning of ventricular activation sequences by ventricular
pressure overload (A) Isochronal map of control E6-6.5 heart with an immature
lateral activation pattern across the dorsal surface of the ventricle. (B) As
in A but the ventral view. (C) As in A but CTB-heart already exhibiting the
apex-to-base activation pattern. (D) As in C but the ventral view with a
mature pattern. (E) Proportion of hearts exhibiting immature (nonapex-to-base,
open bar) and mature (apex-to-base, filled bar) activation patterns following
no operation (control), sham operation and CTB. at, atrium; avj,
atrioventricular junction; ec, endocardium; ivs, interventricular septum; lv,
left ventricle; ot, outflow tract; rv, right ventricle; tb, trabeculum.
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