|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 2. Abnormal cell divisions in sur-6(sv30) embryos. Cell division
patterns (A-F), chromosome segregations during anaphase (G,H) and spindle
orientation (I,J) were examined in wild-type embryos (A,C,E,G,I) or embryos
produced by sur-6(sv30) mothers (B,D,F,H,J). (A-F) Nomarski images.
(A) Wild-type embryo showing normal anaphase spindle in the AB cell. (B)
sur-6(sv30) embryo showing an abnormal L-shaped spindle in the AB
cell. (C) Wild-type embryo in which AB has divided before P1. (D)
sur-6(sv30) embryo in which P1 has divided before AB. (E) Wild-type
embryo showing the orthogonal orientation of the ABar and ABpr spindles.
Doubleheaded arrows indicate the orientation of the spindle. (F)
sur-6(sv30) embryo showing parallel orientation of the ABar and ABpr
spindles. A similar defect has been reported in some Wnt pathway mutants
(Rocheleau et al., 1997;
Thorpe et al., 1997). (G,H)
DAPI staining. (G) Wild-type one-cell embryo showing a normal anaphase figure.
(H) sur-6(sv30) one cell embryo with anaphase bridging defects
(arrow). (I,J) Anti-tubulin staining. (I) Wild-type multicellular embryo
showing two centrosomes per dividing cell. (J) sur-6(sv30)
multicellular embryo showing a dividing cell with supernumerary centrosomes
(arrows).
|
