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Fig. 3. Homozygous dm2/dm2 nurse cells present in mosaic egg chambers exhibit cell-autonomous growth defects. (A,B) The nuclei of dm2/dm2 mutant germ cells, which stain with DAPI but do not exhibit hGFP-associated fluorescence (arrowheads), are significantly smaller than the nuclei of their wild-type sister nurse cells. (C,D) dm2 mutant nurse cell nuclei, visualized with DAPI (arrowheads), often exhibit a blob-like morphology indicating the presence of polytene chromosomes, in the same egg chambers as wild-type nuclei exhibiting the more dispersed polyploid DNA morphology, characteristic of relatively more mature nurse cells.





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