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Fig. 7. Abnormal jaw development in dfna5 morphants. (A-E) Alcian Blue staining of cartilage. (A,C) Lateral (A) and ventral (C) view of a day 5 wild-type larval head. (A) Meckel's cartilage is indicated with a white arrowhead. In C, the ceratobranchials are indicated with 1-5. (B,D,E) Lateral (B) and ventral (D,E) view of a day 5 morphant larval head. (B) Meckel's cartilage (arrowhead) is malformed and the ceratohyal cartilage is inverted, most probably owing to reduction of the branchial cartilages. (E) Cartilage derived from brachial arches 1-5 are present, but strongly reduced. The ceratobranchial cartilage in morphants is less intensely stained than in wild-type. Scale bar: 125 µm in A-D; 200 µm in E.





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