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Fig. 2. Effects of Foxa2-deletion on lung morphogenesis. Triple transgenic mice (SP-C-rtTA-/tg, (tetO)7CMV-Cre-/tg, Foxa2loxP/loxP) and littermate controls were maintained on doxycycline from E0. (A-F) Lung sections of triple transgenic mice and littermate controls were prepared on E18.5 (A,B), PN3 (C,D) and PN16 (E,F) and stained with Hematoxylin and Eosin to assess lung morphology. Figures are representative of at least four individual mice. Scale bar: 300 µm.





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