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Fig. 4. Summary of the observed GMC-1 division phenotypes due to overexpression of miti and or nub. WT, wild type; mitiGOF or nubGOF, overexpression of miti or nub, respectively, for 20 minutes (blue bar) or 90 minutes (green bar). The phenotypes that are specific to 20-minute or 90-minute induction times are marked with same colored short bars. Arrows indicate times at which embryos were analyzed. The unmarked phenotypes were observed in both inductions. Note that a 20-minute induction of miti or nub only in a late GMC-1 (~7.25 hours) induces a symmetrical division of GMC-1 to generate two RP2s (see Mehta and Bhat, 2001). In the UAS-nub; ftz-GAL4 embryo, the UAS-nub transgene was induced with ftz-GAL4 (the ftz promoter is active in GMC-1, see text for details).





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