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Fig. 9. Neurotrophin transcript expression in the mystacial pads of K14-noggin
mice. Expression of neurotrophin mRNAs was analyzed by quantitative RT-PCR
performed with mRNA extracted from the mystacial pads of E14.5 and postnatal
day 2 (P2) K14-noggin and wild-type littermates. Shown are two curves each for
transgenic (blue) and wild-type (red) tissues. At E14.5 there were no changes
in NGF, NT3 or GDNF transcripts, while BDNF transcripts were slightly
increased about twofold in the K14-noggin animals. At PN2 there were no
changes in transcript levels of BDNF, NT3 or GDNF, but there was a small
(fourfold) increase in NGF transcripts in the K14-noggin animals.
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