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Fig. 6. Comparison of membranous bone ossification in the middle ear and jaw joint. Alcian Blue and Alizarin Red stained skeletal preparations. (A-C) Development of the cartilages and bones of the murine middle ear, side view. (D-F).Development of the cartilages and bones of the chick jaw joint, dorsal view. (A) Formation of the malleus and incus at E14. The malleus develops at the proximal end of Meckel's cartilage. There is no bone ossification at this stage. (B) Ossification of the tympanic ring at the base of the malleus at E16. (C) Ossification of the gonium in between the malleus and tympanic ring at E18.5. (D) Formation of the jaw joint between the articular and the quadrate at E7. The articular lies at the proximal end of Meckel's cartilage. (E) Ossification of the angular under the articular and Meckel's at E9. (F) Ossification of the prearticular next to the angular at E13. I, incus; M, malleus; Me, Meckel's cartilage; Ty, tympanic ring; G, gonium; A, articular; Q, quadrate; An, angular; P, prearticular.





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