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Fig. 6. Differential regulation of precursors for proprioceptive and somatic sensory interneurons in r2. Expression of LH2A/B is intact in r2 of E11.5 control (A) and Hoxa2^-/- (B) embryos. Labeling of Lbx1 in r2 of E11.5 control (C) and Hoxa2^-/- (D) embryos shows complete loss of Lbx1 expression in the Hoxa2^-/- embryo. The trigeminal branchiomotoneurons (box), co-labeled with Phox2b (green) and Isl1/2 (red), are intact in the Hoxa2^-/- embryo compared with the littermate control (E,F). Lbx1 expression in r3 of E11.5 control (G) and Hoxa2^-/- (H) embryos shows a significant reduction in the Hoxa2^-/- embryo.

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