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Fig. 3. hfp mutation suppresses the GMR-p21 eye phenotype by promoting cell cycle entry. (A-C) Scanning electron micrographs of adult eyes from wild-type (A), GMR-p21/+ (B) and GMR-p21/+; hfp^EP/+ (C) flies. Scale bar equals 200 µm. (D-L) Eye imaginal discs from wild-type (D,G,J), GMR-p21/+ (E,H,K) and GMR-p21/+; hfp^EP/+ (F,I,L) larvae, co-labelled with BrdU (D-F) and PH3 antibody (G-I). Merged images are shown (J-L). Posterior is to the left. The MF is indicated by a yellow bar and arrows indicate the normal position of the S-phase band posterior to the MF. (M-R) Scanning electron micrographs of adult eyes, to show genetic interactions between p21/Dacapo and dMyc; (M) GMR-p21/+ males, (N) dmycP0/+;GMR-p21/+ females, (O) dmycP0/y; GMR-p21/+ males, (P) GMR-GAL4/+, UAS-dacapo/+, (Q) GMR-GAL4/+; UAS-dmyc/+, (R) GMR-GAL4/+, UAS-dacapo/+; UAS-dmyc/+.

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