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Fig. 6. Normal specification of neural crest progenitor cells in mobm610 embryos. (A,B) In situ hybridization analysis of snail2 (A) and foxd3 (B) expression. The patterns are indistinguishable between wild-type and mobm610 embryos at 10-somite stage. (C,D) sox10 expression at 10- (C) and 20- (D) somite stages is also indistinguishable between wild-type and mobm610 embryos (A-D; wild-type controls not shown). (E,H) crestin expression in wild-type (E,G) and mobm610 embryos (F,H) at 10- (E,F) and 20-somite stages (G,H). Expression of crestin is completely absent in the head (asterisk) of mobm610 embryos and reduced in the trunk. All panels show dorsal views of flat-mount preparations, anterior to the left. The eye (e) and otic vesicle (ov) are marked for orientation.





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