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Fig. 5. The most common axonal phenotype of Zic3 misexpression is that the axons
misrouted to the sub-retinal space at the photoreceptor side. The axons were
photographed at the focal plane of the optic fiber layer (A,C,E). White arrows
indicate the direction toward the optic disc. The same area in A,E was also
photographed with the focal plane at the photoreceptor side to show that some
axons were present at the sub-retinal space (B and F, respectively). The area
shown in D at the photoreceptor side is a little distance away from the area
shown in C. Note that the misrouted axons in the subretinal space were very
disorganized without clear direction. Scale bar: 50 µm.
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