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Fig. 4. Involvement of sotv and botv in Hh signalling. All discs are oriented anterior left, dorsal up. (A-C') Ci staining (red) in a wild-type wing disc (A), and in discs carrying mutant clones of sotv44 (B,B') and botv103 (C,C') in the anterior compartment. The mutant clones are marked by the absence of GFP and are outlined with dots. Within the large clones of sotv44 and botv103, accumulated Ci is seen only in a narrow stripe of cells abutting the AP boundary. (D-F') Hh staining in a wild-type wing disc (D), and in discs carrying mutant clones of sotv44 (E,E') or botv103 (F,F'). The AP boundaries are determined by Ci staining (data not shown) and are marked by lines. Clone boundaries are marked by dotted lines. Hh staining is absent in the clones of sotv44 and botv103, except at a residual level in the posterior-most row of cells adjacent to AP boundary.





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