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Fig. 5. Cardiac and placental abnormalities in endothelium-specific Pdgfb
knockouts. H/E staining shows cardiac (A-D) and placental (E-H) abnormalities
in E18.5 lox/– embryos similar to those seen in
Pdgfb–/– embryos. Arrowheads (B,D) indicate
the thin myocardium typical for –/– and lox/– animals. The
placenta vessels in G and H that could be classified as either maternal or
fetal by their erythrocyte content are outlined in I and J, respectively, to
visualize their dilation in the lox/– animal (maternal sinuses are
colored green, fetal vessels are colored purple). Scale bar in G: 10
µm.
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