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Fig. 2. Postnatal development of the Wnt5a mutant FRT grafts. Wild-type and Wnt5a mutant P0 FRT were cut into fragments along the anteroposterior axis (as indicated) and grafted under the renal capsule of an intact adult host. Grafts were harvested 3 weeks after grafting into the host. Paraffin sections from wild-type (A-D) and Wnt5a mutant (E-G) were stained with Haematoxylin and Eosin. (H-M) High magnification of corresponding boxed area in A-G. All structures formed in the Wnt5a mutant displayed normal characteristics of each compartment, including postnatal smooth muscle (smc) differentiation, stromal compartment (stro) and ciliated epithelium (ci) in the oviduct [inset in K (scale bar: 10 µm)]. Scale bar: 250 µm for low magnification; 50 µm for high magnification. ost, ostium; amp, ampulla.





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