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Fig. 8. Analysis of chondrocyte differentiation in Hif1a conditional
knockout (CKO) mice. Col10a1, Ihh and Pthr1 expression
domains are divided by cells that have lost the expression of these markers in
the growth plates of unaffected (A,C,E) mice, while the Hif1a CKO
(B,D,F) mice cells in the center of the hypertrophic domains express all three
markers.