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Fig. 7. {alpha}vß8 integrin is expressed on white matter axons in the cerebellum. Coronal sections through the cerebellum of a five-month-old Nestin-Cre; {alpha}vflox/+ mouse (A-I) labeled with anti-ß8 antiserum (A,D,G) and anti-neurofilament antibody to visualize axons (B), anti-GFAP antibody to visualize astrocytes (E), or anti-myelin antibody to visualize oligodendrocytes (H). (E,F,I) Merged images. {alpha}vß8 integrin and neurofilament co-localize on white matter axons (C). In white matter regions of the cerebellum, {alpha}vß8 is not detected on GFAP-positive astrocytes (F) or myelinating oligodendrocytes (I).





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