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Fig. 3. Hepatocyte labeling in vav ancestry and lysozyme ancestry mice. (A,B) A binucleated YFP+ hepatocyte (yellow, outlined) in a liver section of a vav ancestry mouse. Nuclei are stained with DAPI (blue) and hematopoietic cells with F4/80, Mac1 and CD45 (purple). Scale bar: 25 µm. (C) The total number and distribution of hepatocyte clusters in vav ancestry mice. (D-F) Liver section of a vav ancestry mouse showing an YFP+ hepatocyte (yellow, outlined) that was stained for albumin expression (red). Nuclei are shown in blue. Scale bar: 10 µm. (G,H) Liver section of a lysozyme ancestry mouse showing a doublet of YFP+ hepatocytes (yellow, outlined). Nuclei are shown in blue; Kupffer cells, stained with F4/80, are in purple. Scale bar: 25 µm. (I) The frequency of YFP+ hepatocyte clusters per 100,000 cells in vav ancestry (vav), lysozyme ancestry (lys) and lck ancestry (lck) mice. Error bars indicate one s.d.





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