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Fig. 1. Domain structures of the retinal determination gene network (RDGN) members. Representative members of the PAX6 (EY), EYA, SIX (SO) and DAC families from Drosophila show the domain structure of RDGN members and their functions. Numbers represent amino acid number; **, conserved MAPK phosphorylation sites in EYA. C, C terminus; DAC, Dachshund; EY, Eyeless; EYA, Eyes absent; EYA D2, EYA domain 2; GRO, Groucho; HDAC3, Histone deacetylase 3; N, N terminus; N-CoR, Nuclear corepressor; P/S/T rich, proline, serine and threonine rich region; SO, Sine oculis.





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