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Fig. 4. Context-dependent relationships between signaling pathways and the retinal determination gene network (RDGN). Positive interactions are shown in green, negative interactions in red. Arrows represent activation or induction; blunt-end lines represent transcriptional and/or post-translational repression. DAC, DACHSHUND; DPP, Decapentaplegic; EGFR, Epidermal growth factor receptor; EYA, Eyes absent; HH, Hedgehog; SHH, Sonic hedgehog; SO, Sine oculis; WG, Wingless.





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