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Fig. 2. Adult eye phenotypes resulting from altering RD gene expression. Photographs of adult eyes, except for E, F and J, which were dissected from unhatched pupae. For clarity, the boundary of eye tissue is outlined in the GMR-Gal4 UAS-AML1-ETO and lz-Gal4 UAS-AML1-ETO flies. Two different driver lines (lz-Gal4, B-F; GMR-Gal4, H-K) were used to express ectopically different fly and mammalian RD proteins. The eye color differences are due to the presence or absence of white (or a mini-white transgene), which is necessary for eye pigmentation. The relevant genotypes of the flies are as follows: (A) wild type; (B) lz-Gal4; UAS-lz; (C) lz-Gal4; UAS-run; (D) lz-Gal4; UAS-AML1; (E) lz-Gal4; UAS-AML1-ETO; (F) lz-Gal4; UAS-lz-enR; (G) lznull; (H) GMR-Gal4; UAS-lz; (I) GMR-Gal4; UAS-run; (J) GMR-Gal4; UAS-AML1; (K) GMR-Gal4 UAS-AML1-ETO.





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