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Fig. 4. The AML1-ETO-induced phenotype is modified by changes in bro, bgb and lz levels. Photographs of adult eyes raised at 22°C (B,C,E-G) and 25°C (A,D,H). The eye tissue of the GMR-Gal4 UAS-AML1-ETO (D) and GMR-Gal4 UAS-AML1-ETO UAS-bro (F) flies is outlined. The eye color differences are due to the presence or absence of white (or a mini-white transgene), which is necessary for eye pigmentation. The genotypes of the flies are as follows: (A) wild type; (B) GMR-Gal4; UAS-bro; (C) bgb^null/+; (D) GMR-Gal4 UAS-AML1-ETO; (E) GMR-Gal4 UAS-AML1-ETO; (F) GMR-Gal4 UAS-AML1-ETO; UAS-bro; (G) GMR-Gal4 UAS-AML1-ETO; bgb^null/+; (H) GMR-Gal4 UAS-AML1-ETO; UAS-lz.

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