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Fig. 1. Expression of Gbx2 in the developing mouse inner ear. (A) Dorsal view of a mouse embryo at 9.5 dpc probed for Gbx2 transcripts. Arrows indicate Gbx2 expression in the otocyst. Arrowheads indicate Gbx2 expression in the mid-hindbrain junction. (B) An enlarged lateral view of the right otocyst in A, showing Gbx2 hybridization signals in the dorsomedial half of the otocyst. (C) Gbx2 expression in the endolymphatic duct (ed) at 10.5 dpc. (D-G) Pairs of 12 µm adjacent sections probed for Gbx2 (D,F) and Bmp4 (E) or Lfng (G) transcripts. Arrows in E indicate Bmp4 expression in the presumptive cristae. Asterisks indicate Gbx2 expression in the neural tube. Approximate levels of sections for C-G are shown in the schematic diagram. Orientation in D applies to D-G; A, anterior; D, dorsal; L, lateral. Scale bar in G applies to D-G.





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